The work of Andrea Büttner includes woodcuts, reverse glass painting, sculpture, video and performance. She creates connections between art history and social or ethical issues, with a particular interest in notions of poverty, shame, vulnerability and dignity, and the belief systems that underpin them.
Büttner's work often makes reference to religious communities, drawing attention to the relationship between religion and art, and between religious communities and the art world. The video Little Sisters: Lunapark Ostia focuses on a sisterhood of nuns who manage an arcade in a small amusement park in Ostia, near Rome. The nuns speak about their work and respond to questions posed by Büttner concerning happiness, spirituality and spectacle.